Drugs in Space, with Will Bruey & Delian Asparouhov (Varda Space)

EPISODE SUMMARY

This week’s Pathfinder pod features Will Bruey (CEO) and Delian Asparouhov (President) of Varda Space Industries. The LA-based startup harnesses microgravity for pharmaceutical development and manufacturing. In its latest mission, the company successfully processed ritonavir, a crucial antiviral drug utilized in HIV/AIDS treatment.

EPISODE NOTES

Right on the heels of their $90M funding round, this week’s Pathfinder spotlights Varda and its cofounders, Will Bruey (CEO) and Delian Asparouhov (President). The LA-based startup harnesses microgravity for pharmaceutical development and manufacturing. In its latest mission, the company successfully processed ritonavir, a crucial antiviral drug utilized in HIV/AIDS treatment.

In addition to Varda’s origin story and the Series B fundraise, Mo, Will, and Delian discuss:

  • Varda’s commercialization strategy
  • The business case for in-space manufacturing
  • The significance of the W-1 mission
  • Adapting to the regulatory environment
  • Microgravity formulation optimization

And much more…

This episode is brought to you by the Italian Trade Agency (ITA).

• Chapters •

00:00 Intro & ITA Ad

01:21 Varda’s origin

05:40 What are you building?

08:17 What does space have to offer for manufacturing?

12:00 The business case for space manufacturing

18:02 What drugs have been improved in space?

19:13 What happened to ZBLAN?

20:54 R&D for manufacturing in space

22:34 The W-1 mission

29:05 Customer traction

30:38 Where does Varda’s business risk lie?

38:22 Competitive landscape

39:49 Potential partnerships

42:48 Regulatory learnings

45:30 The Series B

46:57 Use cases beyond pharma

48:19 Space stations

55:35 Other companies Will is excited about

57:22 Where would Delian invest his last space investment?
 

• Show notes •

Varda’s website — https://www.varda.com/

The Return of Ritonavir Paper: https://www.varda.com/papers/1711063046-return-of-the-ritonavir-a-study-on-the-stability-of-pharmaceuticals-processed-in-orbit-and-returned-to-earth.pdf

Will’s socials — https://twitter.com/WillBruey

Delian’s socials — https://twitter.com/zebulgar

Mo’s socials — https://twitter.com/itsmoislam

Payload’s socials — https://twitter.com/payloadspace / https://www.linkedin.com/company/payloadspace

Pathfinder archive — Watch: https://www.youtube.com/@payloadspace 

Pathfinder archive — Listen: https://pod.payloadspace.com/episodes